城市“腾笼换鸟”产业转型升级的困境与出路——基于北京市的调查研究

剖析北京“腾笼换鸟”产业转型升级的现状,在针对“新鸟”进笼“老鸟”去哪问题,“老笼”空间结构合理优化问题,“老鸟”涅槃“新鸟”培育问题,“老鸟”和“新笼”承接问题的分析基础上,提出应完善京津冀产业链协作,“腾笼换鸟”拓展区域联动发展空间;东西城合并成首都特区,“腾笼换鸟”保护北京历史文化名城;切实发挥政府的职能作用,“腾笼换鸟”提升企业内在动力机制;规划建设“微中心”小城镇,“腾笼换鸟”促进北京人口有效疏解的建议。     

青海湖沙柳河流域浅层地下水不同时期补给特征

地下水稳定同位素组成的时空变化特征可以反映不同时期、不同区域地下水补给来源的差异。通过青海湖沙柳河流域浅层地下水氢氧稳定同位素组成的时空变化特征以及地下水、河水与降雨之间的补给关系的分析，结果显示：季风时期，地下水主要受降雨入渗和河流侧向补给为主，在补给过程中蒸发作用是影响地下水稳定同位素值的主要因素；非季风期，冰雪融水对低值区的地下水影响显著，同时降水的快速入渗则是该时期高值区地下水的主要补给方式之一。地下水同位素高值区，地下水与河水间补给作用较弱，补给时间超过5个月；地下水同位素低值区，地下水与河水补给关系较为密切，补给时间在1~4个月间。本文所得结论可初步反映干旱半干旱内陆流域地下水稳定同位素特征以及补给方式的基本规律，在一定程度上可为流域地下水及其他水体间的转换研究提供科学依据，并为地下水资源管理和水环境治理提供一定理论指导。     

科尔沁湿草甸参考作物蒸散发模拟分析

为探明气候变化下干旱半干旱地区湿草甸参考作物蒸散发(ET₀)影响因子,使用FAO 56 P-M模型对科尔沁湿草甸ET₀进行模拟,利用涡度相关系统对模型的适用性进行评价,并通过通径分析及指标敏感性分析对ET₀的影响因子进行辨识。结果表明:(1)小时尺度模拟精度最高,日尺度次之,月尺度较差,小时尺度上晴、阴、雨3种天气条件下模拟效果不同,晴天最优,阴雨天较差。(2)ET₀年内变化呈单峰曲线状,生长季明显高于非生长季,集中在3—10月,占全年89.79%。生长季典型晴天ET₀逐小时分布特征遵循倒“U”单峰型变化规律。(3)通径分析结果显示,对ET₀的通径系数以及对回归方程估测可靠程度E的总贡献均表现为VPD(饱和水汽压差) > T_min(最低气温) > R_n(冠层表面净辐射)>u₂(2 m高度风速),即VPD为影响ET₀最重要的因子;指标敏感性分析中,在去除VPD后引起的E变化最大,说明ET₀对VPD的变化最为敏感,其次为u₂、T_min和R_n。     

Salinivibrio sp.YH4胞外丝氨酸蛋白酶EYHS耐盐性及生物信息学分析

摘要：目的 探讨菌株Salinivibrio sp.YH4分泌的丝氨酸蛋白酶EYHS的耐盐性及结构特征。方法 明胶底物酶谱法分析EYHS的耐盐性。应用生物信息学手段对EYHS及6种耐盐的S8家族丝氨酸蛋白酶结构特征进行分析。结果 EYHS在4 mol/L的NaCl溶液中仍具有活性，属于耐盐蛋白酶。EYHS及6种S8家族丝氨酸蛋白酶分子表面的loop区等无规则卷曲所占比例较高，α-螺旋与β-片层则主要位于酶分子内部。EYHS分子表面酸性氨基酸含量较高，且具有弱疏水内核。多序列比对发现蛋白酶的催化三联体两侧存在高度保守的基序和保守的极性氨基酸及芳香族氨基酸，并存在多个保守的Gly与Ala。同源模建和表面电荷分布显示，α螺旋和β片层围成了蛋白酶的催化腔，EYHS活性中心包含由Asp32、His65与Ser215组成的催化三联体，且催化位点区域表面静电势为负。结论 上述结构特征可能有助于耐盐丝氨酸蛋白酶EYHS在高盐环境下维持其稳定性和适度柔性，并有助于其催化功能的发挥，为深入研究耐盐丝氨酸蛋白酶的高盐环境适应性提供了一定的理论依据。     

High-P granulites of the Songshugou area (Qinling Orogen,east-central China): Petrography,phase relations,and U/Pb zircon geochronology

High-pressure (HP) granulites provide telling records of mineral reactions at upper mantle to lower crustal levels and key information on the fate of material in subduction systems. The latter especially applies when they abut eclogite and mantle dunite because such rock associations are crucial for understanding the incompletely known processes at the interface of converging plates. A continental arc, active c. 520–395 Ma ago, formed an enigmatic example of such a rock association in the Songshugou area, Qinling Orogen. To unravel the juxtaposition of the distinct rocks, this study combines petrography, phase equilibria modelling, conventional thermobarometry, and zircon U–Th–Pb–Ti–REE analysis. Two mafic HP granulites, which contain the mineral assemblages garnet–clinopyroxene–plagioclase–rutile–mesoperthite–quartz and garnet–clinopyroxene–plagioclase–rutile, experienced peak metamorphic conditions of ≤1.4 GPa, 860°C and ~1.3 GPa, ≥910°C, respectively. During decompression and cooling, at 489 ± 4 Ma, amphibole lamellae unmixed from a clinopyroxene solid solution and orthopyroxene in part replaced garnet. A felsic HP granulite shows equilibration of garnet, perthite, antiperthite, kyanite, quartz, and rutile at 810–860°C, ~1.2 GPa, sillimanite growth during decompression, and upper amphibolite facies cooling at 510 ± 4 Ma. Though the thermobarometric data are just within the methodological errors, the U/Pb zircon ages imply the HP granulites did not evolve coherently. The HP granulites either represent foundered lower arc crust or originated from subduction erosion because their geochemistry is indistinguishable from that of the hanging-wall plate. Published and new pressure–temperature–time–deformation paths converge at ~710°C, ~0.9 GPa, and ≲470 Ma, implying exhumation tectonics juxtaposed the HP granulites with a mélange of eclogite and mantle dunite at lower crustal levels. This study highlights that lower arc crust can comprise material of diverse evolution.     

艾灸对实验性RA家兔IL-10、IL-17、OPN的影响

目的：观察艾灸对实验性类风湿性关节炎（RA）家兔外周血中白细胞介素（IL）-10、IL-17及骨桥蛋白（OPN）表达的影响，并探索艾灸治疗RA的抗炎机制。方法：选取日本大耳白兔30只，将其随机分为空白组、模型组、治疗组，每组各10只，采用福氏完全佐剂法制备实验性RA模型。在造模后第7天，治疗组采用悬灸肾俞、足三里穴疗法，每穴各灸5壮，　1次/d，以6d为1个疗程，共干预3个疗程。检测各组血清中IL-10、IL-17及OPN的含量。结果：IL-10、IL-17、OPN模型组与空白组比较，治疗组与模型组比较，差异均有统计学意义（P<0.01）。结论：艾灸治疗对实验性RA家兔有显著的抗炎作用，可有效降低血清IL-17及OPN含量，上调IL-10的表达，其抗炎的作用机制可能是通过调节OPN的表达，进而调节Th17/Treg而实现的。     

青海湖盆地史前狩猎采集人群的石料利用策略研究

史前人类向青藏高原扩散的过程和适应高海拔缺氧环境的机制是多学科关注的热点科学问题.青海湖盆地是青藏高原旧石器-中石器时代遗址分布最为丰富的区域,对这些遗址出土的石制品原料的分析有助于深入理解青藏高原史前狩猎采集人群的石料开发策略、人群迁徙和交流联系.青海湖盆地151遗址出土的928件石制品的石料研究分析显示,处于末次冰消期的下文化层的石制品以近源的石英和石英岩为主要原料,而处于全新世早中期的上文化层在同类型近源石料仍占主体地位的情况下,开始出现较高比例和多样化的优质硅质石料,并且主要用于生产细石器.野外调查和查阅地质资料均未发现青海湖盆地内有151遗址中出现的同类型优质硅质石料产出,推测其来自远距离搬运.青海湖盆地内其他8个末次冰消期至全新世中期遗址的3269件石制品石料分析结果显示,与151遗址同类型的远源优质硅质石料在全新世早期开始在盆地内的遗址中出现.这一结果表明青海湖盆地末次冰消期古人类活动强度和范围有限,全新世早中期古人类受到全新世大暖期气候变好和周边地区农业人群兴起挤压活动空间的双重影响,在高原上的活动范围和强度大大增加,伴随着开始有意识地开发优质石料,较频繁地进行远距离迁移和人群交流.远源优质硅质石料的产地可能位于北祁连山区和青藏高原上的陆相火山岩区,需要未来更深入的研究揭示.该研究为深入理解青藏高原古人类的高海拔环境适应策略和移动模式提供了重要材料,为理解史前人类向高原扩散的机制提供了重要信息.     

Building a model-based personalised recommendation approach for tourist attractions from geotagged social media data

When travelling, people are accustomed to taking and uploading photos on social media websites, which has led to the accumulation of huge numbers of geotagged photos. Combined with multisource information (e.g. weather, transportation, or textual information), these geotagged photos could help us in constructing user preference profiles at a high level of detail. Therefore, using these geotagged photos, we built a personalised recommendation system to provide attraction recommendations that match a user's preferences. Specifically, we retrieved a geotagged photo collection from the public API for Flickr (Flickr.com) and fetched a large amount of other contextual information to rebuild a user's travel history. We then created a model-based recommendation method with a two-stage architecture that consists of candidate generation (the matching process) and candidate ranking. In the matching process, we used a support vector machine model that was modified for multiclass classification to generate the candidate list. In addition, we used a gradient boosting regression tree to score each candidate and rerank the list. Finally, we evaluated our recommendation results with respect to accuracy and ranking ability. Compared with widely used memory-based methods, our proposed method performs significantly better in the cold-start situation and when mining ‘long-tail’ data.     

基于引文分析法的“点-轴系统”理论研究述评

论文采用引文分析法,对陆大道院士所著《关于“点-轴”空间结构系统的形成机理分析》一文的349篇引文进行分析,从引文数量、引文作者、发文期刊、研究案例地、学科领域、研究主题、引用动机7个方面,探究“点-轴系统”理论的研究现状。结果表明：自2002年以来,“点-轴系统”理论的引文数量整体呈上升趋势,研究主题聚焦于区域经济和旅游发展;研究案例地以省级和市级中观尺度为主,多为单一型研究区,主要集中在西北丝绸之路经济带、东北辽宁经济圈、西南藏滇川渝、东部长三角四大热点区域;引文质量普遍较高,并且具有多学科交叉应用的特点,但批判性思考和创造性提升相对较少。基于此,论文从拓展研究和实践应用2个角度对“点-轴系统”理论未来发展进行了展望,以期为相关研究提供参考。     

Prediction of the South China Sea Dipole Using SSA-MEM

ABSTRACT

A dipole structure appears in the sea surface height off the central coast of Vietnam during boreal summer in the South China Sea. This dipole, which possesses a chlorophyll signature associated with higher phytoplankton concentrations arising from nutrient upwelling, is important for the productivity of local fisheries. Multi-satellite sea level anomalies are used to investigate the life cycle of the dipole structure. By applying empirical orthogonal function (EOF) analysis, the third EOF mode (EOF 3) is found to represent the major variations of the dipole structure. By removing the temporal noise of EOF 3, a South China Sea dipole index is defined. This index captures the life cycle of the dipole including its generation, mature strength, and final termination. Both one-dimensional and two-dimensional forecasts are generated using a statistical forecasting method that combines singular-spectrum analysis and the maximum entropy method. The appearance of the dipole structure can be predicted with an accuracy of 78% at one-month lead times and an accuracy of 61% at one-year lead times.